Tests on nutrigenetics and nutrigenomics
What nutrigenetic and nutrigenomic tests do we offer?
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What is nutrigenetics and what is it for?
Nutrigenetics is the branch of genetics that studies the relationship between genes and diet with the aim of achieving optimal health through diet. We all know that an incorrect diet can be the cause behind numerous health problems such as: overweight, autoimmune diseases, inflammatory diseases, cardiovascular diseases, cancer… In addition, there are certain types of food intolerances or allergies whose cause may also be genetic.
Nutrigenetic tests analyse certain DNA variants related to important aspects of metabolism such as fat accumulation and increased BMI (Body Mass Index), appetite regulation, the metabolism of certain vitamins and other variants important for the development of a personalised diet, as well as those variants associated with food intolerances or allergies.
What nutrigenetic and nutrigenomic tests do we offer at Genosalut?
At Genosalut we offer different genetic tests within the field of nutritional genomics, from those focused on the analysis of one or a few variants to the complete study of the genome.
If there is a suspicion of a specific metabolic problem or food intolerance (e.g. lactose or fructose), the genetic variants associated with the problem can be specifically analysed.
It involves the analysis of multiple genetic variants involved in the development of food intolerances, the adoption of addictive behaviours that increase the need for food intake, the metabolic response to fats, carbohydrates and vitamins, the development of obesity and the response to exercise.
Sequencing of all genes by next generation sequencing (NGS) to determine the presence of variants associated with metabolic problems.
Sequencing of all coding (gene) and non-coding regions by next generation sequencing (NGS) to determine the presence of variants associated with metabolic problems.
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What is the difference between nutrigenetics and nutrigenomics?
Nutrients are able to interact with molecular mechanisms and modulate physiological functions in the body. Nutritional genomics focuses on the interaction between the bioactive components of food and the genome, and includes nutrigenetics and nutrigenomics.
The terms nutrigenetics and nutrigenomics are sometimes used synonymously although they actually have different meanings:
- Nutrigenetics examines how your body responds to nutrients based on your genetics. In other words, nutrigenetics describes that the genetic profile has an impact on the body’s response to bioactive food components by influencing their absorption, metabolism and site of action. In addition, it analyses genetic variants (polymorphisms or SNPs) in DNA that are associated with nutrition-related diseases.
- Nutrigenomics studies how nutrients affect gene expression. In other words, nutrigenomics provides a genetic understanding of how common dietary components affect the balance between health and disease by altering the expression and/or structure of an individual’s genetic make-up.
Frequently asked questions
Today, the general recommendations for a healthy and balanced diet that allows us to obtain the appropriate amounts of each type of nutrient are well known. However, the same diet can have different effects on different individuals. For example, even if two people eat in the same way, it may happen that one of them gains weight and the other does not. This is because, among other things, the recommendations that serve as a general guideline for the entire population do not take into account a factor that makes us unique: our DNA. In fact, it is estimated that genetic factors account for between 40 and 70% of the variability associated with metabolism and although we do not know the total number of genes involved, we do know some that play a relevant role.
A nutrigenetic test is a test that allows us to learn a little more about our DNA in order to adapt our diet to our needs.
Genetic differences can not only condition nutritional needs but also predispose to different pathologies of multifactorial origin, those in which both genetics and the environment play an important role.
Medicine is undergoing a transformation process focused on achieving preventive (proactive rather than reactive) and personalised medicine (applying individualised rather than generalised measures, therapies and treatments). This is increasingly based on informed decisions.
Within this stream of prevention and personalisation, genetics is becoming increasingly important. Within the branches of genetics, nutrigenetics makes it possible to adapt nutrition to each individual according to his or her genes, to be healthier and to take measures to prevent diseases.
Knowing ourselves is the first step towards taking control of our diet and our health.
Genetics is a complex field when you do not have basic knowledge, and nowadays there are many offers that lack scientific evidence and/or can confuse people. For this reason, it is always best to request this type of test through a specialist who can guide you and give you realistic expectations about the information you will receive.
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